Facts about necrotizing fasciitis and septic shock

 Necrotizing fasciitis (NF) is a rare, life-threatening infection resulting in necrosis of the skin, subcutaneous tissue, and fascia. Mortality rates have been noted as high as 73 percent. Certain conditions can predispose patients to NF, such as diabetes mellitus, immunosuppressive medications, and AIDS.

The medical treatment of NF varies according to the type of bacteria, location(s) of the body affected, and other factors. Generally, however, treatment includes:

  • Surgical Debridement (multiple often required)
  • Broad Spectrum Antibiotic Therapy (tailored with culture) include Clindamycin, Vancomycin, Penicillin, etc.
  • Amputation
  • Induced Sedation & Ventilation
  • VAC (Vacuum Assisted Closure) –  removes chronic edema, leading to increased localized blood flow, enhanced formation of granulation tissue.
  • Treatment for Complications (toxic shock, organ failure, respiratory distress)
  • IVIG – Intravenous Immunoglobulin (not standard – but has proven effective)
  • Aggressive wound care and repeated lab tests
  • Hyperbaric Oxygen Therapy (not standard – but has proven effective)
  • Skin Grafts, Home Care
  • Physical Rehabilitation, Prosthesis, Psychological, and Social Support
Many who do survive are left with life-changing effects, such as post-traumatic stress disorder (PTSD), chronic pain and fatigue, and organ dysfunction (organs don’t work properly) and/or amputations.
 The ten year survival rate is that 87 percent of surviving patients die with that ten year span due to infection including pneumonia, flu, and the cold. Female survivors are 65 percent more likely to die then male.
Post-sepsis syndrome is a condition that affects up to 50% of sepsis survivors. They are left with physical and/or psychological long-term effects, such as:

Insomnia, difficulty getting to sleep or staying asleep
Nightmares, vivid hallucinations and panic attacks
Disabling muscle and joint pains
Extreme fatigue
Poor concentration
Decreased mental (cognitive) functioning
Loss of self-esteem and self-belief
The risk of having PSS is higher among people who were admitted to an intensive care unit (ICU) and for those who have been in the hospital for extended periods of time. PSS can affect people of any age, but a study from the University of Michigan Health System, published in 2010 the medical journal JAMA, found that older severe sepsis survivors were at higher risk for long-term cognitive impairment and physical problems than others their age who were treated for other illnesses. Their problems ranged from not being able to walk, even though they could before they became ill, to not being able to do everyday activities, such as bathing, toileting, or preparing meals. Changes in mental status can range from no longer being able to perform complicated tasks to not being able to remember everyday things.

Necrotizing fasciitis affects 0.4 to 1 person per 100,000 per year. To explain that: 
Notable cases[edit]
1994 Lucien Bouchard, former premier of Québec, Canada, who became infected while leader of the federal official opposition Bloc Québécois party, lost a leg to the illness.[24]
1994 A cluster of cases occurred in Gloucestershire, in the west of England. Of five confirmed and one probable infection, two died. The cases were believed to be connected. The first two had acquired the Streptococcus pyogenes bacteria during surgery, the remaining four were community-acquired.[25] The cases generated much newspaper coverage, with lurid headlines such as “Flesh Eating Bug Ate My Face”.[26]
1997 Ken Kendrick, former agent and partial owner of the San Diego Padres and Arizona Diamondbacks, contracted the disease in 1997. He had seven surgeries in a little more than a week and later recovered fully.[27]
2004 Eric Allin Cornell, winner of the 2001 Nobel Prize in Physics, lost his left arm and shoulder to the disease in 2004.[28]
2005 Alexandru Marin, an experimental particle physicist, professor at MIT, Boston University and Harvard University, and researcher at CERN and JINR, died from the disease.[29]
2006 Alan Coren, British writer and satirist, announced in his Christmas 2006 column for The Times that his long absence as a columnist had been caused by his contracting the disease while on holiday in France.[30]
2009 R. W. Johnson, South African journalist and historian, contracted the disease in March 2009 after injuring his foot while swimming. His leg was amputated above the knee.[31]
2011 (January) Jeff Hanneman, guitarist for the thrash metal band Slayer, contracted the disease in 2011. He died of liver failure two years later, on May 2, 2013, and it was speculated his infection might be the cause of death. However, on May 9, 2013, the official cause of death was announced as alcohol-related cirrhosis. Hanneman and his family had apparently been unaware of the extent of the condition until shortly before his death.[32]
2011 Peter Watts, Canadian science fiction author, contracted the disease in early 2011. On his blog, Watts reported, “I’m told I was a few hours away from being dead…If there was ever a disease fit for a science fiction writer, flesh-eating disease has got to be it. This…spread across my leg as fast as a Star Trek space disease in time-lapse.”[33]
2014 Daniel Gildenlöw, Swedish singer and songwriter for the band Pain of Salvation spent several months in hospital after being diagnosed with necrotizing fasciitis on his back in early 2014. After recovering he went to write the album ‘In the Passing Light of Day’,[34] a concept album about his experience during the hospitalization.[35]
2014 Don Rickles (d. April 6, 2017), an American stand-up comedian, revealed on The Late Show with David Letterman on 2 May 2014 that he had contracted necrotizing fasciitis on his right leg. His doctor came over to his house for a visit and noticed a sore on Don’s leg. After examining it he sent him straight to the hospital. Treatment was successful, though he now requires a cane for a short period of time. If it had progressed further, Don quipped, he would have wound up with Johnny Depp as a one legged pirate.[36]
2015 (May) Edgar Savisaar, an Estonian politician. His right leg was amputated. He got the disease during a trip to Thailand.[37]

In 2015 there were an estimated 312 million people in the united states.

That means 3120 of them had NF. 2227 people DIED from it in that year.

Only 893 of them lived. Of that 893 , 776 of them are dead in ten years time, after fighting for their lives.

That means, only 117 of them live past that decade mark.


Am I going to be one of them?

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